BÖLÜM 1/A 10. Knight JA. Disease related to oxygen-derived free radicals. Ann Clin Lab Sci. 25: 111-21, 1995. 11. Riley PA. Free radicals in biology: oxidative stress and the effects of ionizing radiation. Int J Radiatr Biol. 65: 27-33, 1994. 12. Snyder JW. Mechanisms of toxic cell injury. Clin Lab Med. 10: 311-21, 1990. 13. Lubec G. The hydroxyl radical: from chemistry to human disease. J Invest Med. 44: 324-46, 1996. 14. Farber JL, Kyle ME, Coleman JB. The mechanism of cell injury by activated oxygen species. Lab Invest. 62: 670-9, 1990. 15. Stadtman ER, Bertlett BS. Reactive oxygen-mediated protein oxidation in aging and disease. Chem Res Toxicol. 10: 485-94, 1997. 16. Coon MJ Vaz AD, Bestervelt LL. Cytochrome P450: peroxidative reactions of diversozymes. FASEB J. 10: 428-34, 1996. 17. Farber E, Liang H, Shinozuta H. Dissociation of effects on protein synthesis and ribosomes from membrane changes induced by carbon tetrachloride. Am J Pathol. 64: 601-17, 1971. 18. Cohen SD, Khairallah EA. Selective protein arylation and acetaminophen-induced hepatoxicity. Drug Metab Rev. 29; 5977, 1997. 19. Majno G, Joris I. Apoptozis, oncosis, necrosis: An overview of cell death.. Am J Pathol. 146: 3-15, 1995. 20. Kerr JFR, Wyllie AH, Currie AR. Apoptozis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer. 26: 239-57, 1972. 21. Wyllie AH, Morris RG, Smith AL, Dunlop D. Chromatine cleavage in apoptozis: association with condensed chromatin morphology and dependence on macromolecular synthesis. J Pathol. 142: 67-77, 1984. HÜCRE ZEDELENMES‹ VE HÜCRE ÖLÜMÜ 27 22. Salvesen GS, Dixit VM. Caspases: intracellular signalling by proteolisis. Cell. 91: 443-6 1997. 23. Hengartner MO, Horvitz HR. Programmed cell death in Caenorhabditis Elegans. Curr Opin Genet Dev. 4: 581-6, 1994. 24. Webb SJ, Harrison DJ, Wyllie AH. Apoptozis an overview of the process and its relevance in disease. Adv Pharmacol. 41: 1-34, 1997. 25. Darmon AJ. Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B. Nature. 377: 446-8, 1995. 26. Gotzman J, Vlcek S, Foisner R. Caspase-mediated cleavage of the chromosome-binding domain of lamina-associated polypeptide 2 alpha. J Cell Sci. 113; 21: 3769-80, 2000. 27. Nemes Z, Friies R, Aeschlimann D, Saurer S, Paulson M, Fesus L. Expression and activation of tissue transglutaminase in apoptotic cells of involuting rodent mammary tissue. Eur J Cell Biol. 75: 125-33, 1996. 28. Savill J. Recognition and fagocytosis of cells undergoingb apoptozis. Br Med Bull. 53: 491-508, 1997. 29. Gavrielli Y, Sherman Y, Ben-Sason SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol. 119: 493-501, 1992. 30. Frankfurt OS, Krishan A. Identification of apoptotic cells by formamide-induced DNA naturation in condensed chromatin. J Histochem Cytochem. 49: 369-78, 2000. 31. Kerr JFR, Winterford CM, Harmon BV. Apoptozis: its significance in cancer and cancer therapy. Cancer. 73: 2013-26, 1994. 32. Roy N, Mahadevan MS, McLean M, Shutler G, Yaraghi Z, Farahani R, et al.The gene for neuronal apoptozis inhibitory protein is partially deleted in individuals with spinal muscular atrophy. Cell. 80: 167-78, 1995.