Refer to www.wpiinc.com/myocyte or request the new Muscle Physiology catalog for details on the complete line of muscle physiology equipment and accessories. Compact Langendorff M U SCLE PHYS IOLOGY Miniature system for isolated, perfused heart/ischemia reperfusion studies l Capability of measuring: left ventricular pressure (LVP), perfusion or aortic pressure, coronary flow, buffer temperature, heart rate (HR), muscle surface potentials, monophasic action potentials (MAP), muscular tone and force using optional force-displacement method l Port on aortic cannula for administering drugs l Optional capability of pacing/ stimulating the heart l Optional capability of imaging calcium distribution in a functioning heart Patent Pending . U .S . and international patent applications filed . l In vitro studies of isolated hearts from small animals (mouse, rat, guinea pig, rabbit) l Retrograde perfusion (Langendorff) or working heart (Janicki) technique l Constant pressure or constant flow mode l Occupies a small amount of bench space and no tall buffer columns l Perfusion pressure electronically controlled at desired value between 0 and 500mmHg l Highly stable environment for maintaining heart at desired temperature with integrated temperature control system that can be set at 0 .1°C increments l Buffer reservoirs can be configured to form one large (2L), two medium (1L each) or four small (500mL each) volumes of perfusion fluid l Unique heart suspension module permits easy attachment of the heart to the system, and the concise placement of the heart within the optional monophasic action potential (MAP) sensor COMPACT LANGENDORF SYSTEM SI-LANGC Compact Langendorf Working Heart System System includes: Thermostatically controlled unit with built-in heaters (2), reservoirs, tap valves, heart suspension cannula, heart chamber, oxygenation system, pressure transducers with cables (2), 2-channel pressure sensor amplifier, pressure controller, temperature controller, catheter balloons, Peristar-Pro high output peristaltic pumps (2) OPTIONAL COMPONENTS SI-SEN12AM4E-U Manipulator with Removable Head (Unipolar) SI-SEN12AM4E-B Manipulator with Removable Head (Bipolar) SI-SEN07RTH2 Buffer Temperature Sensor SI-SEN13MAP Monopolar Action Potential Sensor World Precision Instruments UK: Tel: +44 (0)1462 424700 • wpiuk@wpi-europe.com www.wpiinc.com Germany: Tel: +49 (0)30-6188845 • wpide@wpi-europe.com US: Tel: 941-371-1003 • sales@wpiinc.com 7