Refer to www.wpiinc.com/myocyte or request the new Muscle Physiology catalog for details on the complete line of muscle physiology equipment and accessories. Cell Tester System The SI-CTS system is a revolutionary new research tool for studying single living cells . This system, which is the result of blending the latest technologies in electronics, mechanics and optics, permits researchers to investigate living systems at a new level using an innovative experimental paradigm . The Cell Tester provides researchers with the comprehensive ability to investigate and characterize the physiological, biomechanical and biophysical properties of single isolated living cells, and to extend these findings to both the sub-cellular and multicellular levels . The SI-CTS systems can be used on single living cells, small multi-cellular preparations or skinned muscle fibers and strips without modification . It is designed to sit on the stage of any standard, research-level, inverted microscope while maintaining the optical path of the microscope for simultaneous fluorescence or confocal imaging . The Cell Tester is an integrated system of components needed to maintain and handle single living cells, stimulate and perform pertubations of the cells, and detect, amplify, and record signals, like contractile force, from the cells . l Optical transducer for measuring force with nN sensitivity and integral microtweezers for facilitating cell attachment . Lifetime warranty on optical heads . l Equipped with a nanomotor for stretching and relaxing cell with nm resolution and integral microtweezers for handling cells l A rotating cuvette system for easy alignment of cells with the microtweezers increases M U SCLE PHYS IOLOGY productivity . Interchangeable bath inserts simplify the coating of cell mounting devices and the handling of live cells . l Signal conditioning amplifier system includes a force transducer amplifier with multiple gains, a position controller for moving the nanomotor used to stretch and relax cells and to open and close the microtweezers, a 2-channel temperature controller, and an anti-oscillation unit for eliminating the resonance frequency of the transducer and its mounting support . l Labtrax 8/16 data acquisition system with MDAC software records force signals, motor positions and other data through four analog inputs . It is designed for controlling the stimulator and the position of the linear motor through two analog outputs and other devices through two digital outputs . l Includes non-cytotoxic bioadhesive (MyoTak™) that facilitates bonding of cell to measuring device SI-CTS200 Complete Cell Tester System System includes: Force transducer and nanomotor with microtweezers, rotating cuvette system, motorized micromanipulators with pedestal bases, signal conditioning system with transducer amplifier, anti-oscillation module, position/ motor control module and temperature control module, data acquisition system with MDAC software for recording, controlling stimulation and nanomotor position, and MyoTak™ bioadhesive kit (5 week supply) . The rotating cuvette allows for precise positioning of the cells to be mounted, and it includes two interchangeable inserts. The first holds any 35mm glass bottom dish for use when coating tweezers or glass rods with MyoTak. Use the native cuvette insert for the live cells. World Precision Instruments UK: Tel: +44 (0)1462 424700 • wpiuk@wpi-europe.com A single rat cardiac myocyte is held by MyoTAKcoated glass rods on the Cell Tester. www.wpiinc.com Germany: Tel: +49 (0)30-6188845 • wpide@wpi-europe.com US: Tel: 941-371-1003 • sales@wpiinc.com 3