“Super” Adhesives for Life Science Research Cyanoacrylate adhesives have been on the market since 1958. Most with the traditional suture, industrial or household grade cyanoacrylate is made of shorter alkyl the new super adhesive chain derivatives such as methyl or ethyl cyanoacrylate (WPI’s #7341 has several advantages. and #7342). They are very useful for temporarily holding tissues such On average, it takes only as mounting specimens for microtome sectioning. However, they are not one-tenth of the time suitable for bonding wounds on live animals. The difficulties of using to close an incision. The cyanoacrylate for bonding live animals are: (1) a strong, irritating odor; bonding strength is equal (2) quick loss of bonding strength due to breakdown of the bonding by to 5-0 monofilament suture. hydration; (3) the breakdown products, cyanoacetate and formaldehyde, It also has a mysterious are toxic and can cause inflammatory reactions; and (4) they have low antimicrobial effect that flexibility and tend to be brittle. can decrease infection rates in contaminated wounds. To overcome these problems, several longer alkyl chain cyanoacrylates Bonding will slough off have been developed especially for veterinary and human use. The first naturally in 5 to 7 days. longer alkyl chain product Cosmetic appearance of the is butyl cyanoacrylate. This healed incision is also better. product has been used for animal and human Gluture Topical Tissue Adhesive #503763 forms a strong and flexible applications outside the USA film and is thus more suitable for surface wound bonding, protection, and since 1970. It is much less holding a sensor or other device on the tissue. Setting time is about 10 toxic and has a lower odor seconds, which gives ample time for application. It can also be used for than the methyl or ethyl temporarily holding a live tissue. For example, there is a report of using it cyanoacrylate. The butyl to hold nematodes on a glass slide for patch-clamp neurons recording. cyanoacrylate offered by WPI All of the products offered by WPI are veterinary grade (not suitable for is Vetbond™. human application). Though very similar to the grade for human use, they A family of adhesives are not sterile and do not have FDA approval. containing octyl cyanoacrylate, a plasticizer and 503763 Gluture Topical Tissue Adhesive (10 tips), 1.5 mL stabilizer, was developed In the 1990’s (one of them 7341 Cyanoacrylate Adhesive, low viscosity—90-120 cps (package of 10 vials, each approx 1.5mL) approved by FDA for human use). When bonding to 7342 Cyanoacrylate Adhesive, high viscosity—1100-1600 cps (pkg of 10 vials, each approx 1.5mL) tissue, these new adhesives are four times stronger VETBOND 3M Vetbond™ Adhesive (3 mL) and less toxic than butyl cyanoacrylate. Compared Sylgard LAB SUPPLIES A two-part silicone elastomer, ideal for potting and encapsulating applications. Very low dielectric constant sealing compound used in patch clamping and many other lab applications. After cure, will withstand -55° to 200 °C. Shipping weight: 2 lb. (1 kg) Silicone Dissecting Pad Kit SYLG184 Sylgard (1.1 lb) Lab Coat LABCOAT-XS LABCOAT-S LABCOAT-M LABCOAT-L LABCOAT-XL Lab Coat, Extra Small Lab Coat, Small Lab Coat, Medium Lab Coat, Large Lab Coat, Extra Large Light weight, medium length — for the lab professional SOLD OUT! Make your own silicone dissecting pads easily and quickly. Mix the 2-part silicone right in the plastic petri dishes and allow to cure 24 hours at room temperature. Kit includes enough silicone to prepare 20 dishes. Kit Includes: 2-Part Sylgard silicone elastomer 20 plastic petri dishes with lids, 65mm Pins 501986 Silicone Dissecting Pad Kit Quantity discount available 102 World Precision Instruments UK: Tel: +44 (0)1462 424700 • wpiuk@wpi-europe.com www.wpiinc.com Germany: Tel: +49 (0)30-6188845 • wpide@wpi-europe.com US: Tel: 941-371-1003 • sales@wpiinc.com