![]() bleau 3) impliquant un faible risque. également insuffisant, on peut envisa- ger un soutien médicamenteux. Pour un aperçu des preuves scientifiques et des recommandations internatio- nales, nous vous renvoyons au ta- bleau 5. Dans un souci d'exhaustivité, nous vous présentons également un aperçu des preuves scientifiques et des recommandations pour les pa- tients souffrant d'un trouble bipolaire. actuelle relative à l'augmentation du risque d'affections cardiométaboliques chez les sujets dépressifs, on a tout intérêt à bien suivre le fonctionnement somatique des patients dépressifs, surtout en cas d'uti- lisation prolongée d'ATC et d'antipsycho- tiques. En cas d'anomalies métaboliques, il faut en premier lieu adresser le patient à des soins plus spécialisés. Si ces soins s'avèrent insuffisants, il faut envisager de changer d'antidépresseur ou d'antipsycho- tique, ou encore envisager un soutien mé- dicamenteux complémentaire. 1. men van depressie in België. Stand van zaken en reflec- ties voor de toekomst. Tijdschr Psychiatrie 2008; 50(10):655-65. years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012;380(9859):2197-223 disease. A review and meta- analysis Am J Prev Med 2002;23:51-61. syndrome and metabolic abnormalities in patients with major depressive disorder: a meta-analysis of prevalences and moderating variables. Psychol Med 2013; geaccept- eerd voor publicatie. ditions mediate the association between depression and cardiovascular disease mortality. Soc Psychiatry Psychiatr Epidemiol 2012;47(4):615-25. pressive disorder predicts completion, adherence, and outcomes in cardiac rehabilitation: a prospective cohort study of 195 patients with coronary artery disease. J Clin Psychiatry 2011;72(9):1181-8. pressive syndromes be reclassified as «metabolic syn- drome type II»? Ann Clin Psychiatry 2007;19(4): 257-64. pathophysiologic cal analysis. Biol Psychol 2007;74:200-11. DH, McConnell H. Mind and heart: heart rate variability in major depressive disorder and coronary heart disease - a review and recommendations. Aust N Z J Psychiatry 2012;46(10):946-57. itary-adrenal activation: a quantitative summary of four decades of research. Psychosom Med 2011;73(2):114-26. Cortisol responses to mental stress and the progression of coronary artery calcification in healthy men and women. PLoS One 2012;7(2):e31356. analysis of cytokines in major depression. Biol Psychiatry 2010;67:446-57. sion: A systematic review and meta-analysis of longitudi- nal studies.. J Affect Disord 2013; doi:pii: S0165- 0327(13)00477-1. 10.1016/j.jad.2013.06.004. factor alpha (TNF-) and soluble interleukin-2 receptors (sIL-2R) are elevated in patients with major depressive disorder: a meta-analysis and meta-regression. J Affect Disord 2012;139(3):230-9. 853-9. platelet function, and ischemic heart disease. Psychosom Med 2005;67(Suppl 1):34-6. genetic factors in the co-occurrence of symptoms of de- pression and cardiovascular risk factors. J Affect Disord 2010;122(3):247-52. cial factors, and genetics: the case of depression. Prog Cardiovasc Dis 2013;55(6):557-62. immune genes in the association between depression and inflammation: a review of recent clinical studies. Brain Behav Immun 2013;31:31-47. bruik van antidepressiva en Antipsychotica. 2013; Rijk- sinstituut voor ziekte- en invaliditeitsverzekering. Website http://www.riziv.be/information/nl/studies/study61/pdf/ studie61.pdf geraadpleegd op 21 augustus 2013. lines in America and Europe. J Clin Psychiatry 2010; 71(Suppl E1):e04. sants needed for psychotic depression? A systematic re- view and meta-analysis of trials comparing antidepres- sant or antipsychotic monotherapy with combination treatment. J Clinical Psychiatry 2012;73(4):486-96. tween conventional antidepressants and the metabolic syndrome: a review of the evidence and clinical implica- tions. CNS Drugs. 2010;24(9):741-53. patients with severe mental disorders. I. Prevalence, im- pact of medications and disparities in health care. World Psychiatry 2011;10:52-77. cal care for people with and without comorbid mental illness and substance misuse: systematic review of com- parative studies. Br J Psychiatry 2009;194(6):491-9. handeling van cardiovasculaire risicofactoren bij behan- deling met antipsychotische medicatie. Neuron 2012;17(5):1-6. disease and diabetes in people with severe mental illness position statement from the European Psychiatric Associ- ation (EPA), supported by the European Association for the Study of Diabetes (EASD) and the European Society of Cardiology (ESC). Eur Psychiatry 2009;24(6):412-24. guidelines on cardiovascular disease prevention in clini- cal practice: executive summary. Eur J Cardiovasc Prevent Rehabil 2007;14(Suppl 2):E1-E40. en met antipsychotica: screening en follow-up. Neuron 2013;18(1):1-5. nadian Network for Mood and Anxiety Treatments (CAN- MAT) task force recommendations for the management of patients with mood disorders and comorbid metabolic disorders. Ann Clin Psychiatry 2012;24(1):69-81. patients souffrant d'un trouble bipolaire et de dépression majeure (31). Trouble bipolaire |