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78
FiFtEENtH NatiONal CONFERENCE
WEdNEsday 15 may
4:30 ­ 5:00Pm
Concert Hall
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ReseaRch
CaN asPiRiN slOW COgNitivE
dECliNE aNd tHE ONsEt OF
dEmENtia? tHE asPREE study
Mark Nelson
ASPREE is a large-scale (N = 19 000)
randomised placebo controlled primary
prevention trial of low dose aspirin for
extending healthy active life in those aged
70 years or more (defined as alive, free
of dementia and persistent disability). It
is sponsored by the NIH and NHMRC.
Recruitment is community-based in the
US and general practice-based in Australia.
Participants are aged 70 years+ (65+
US minorities), free of cardiovascular
disease, dementia, disability, any absolute
contraindication or allergy to aspirin or any
illness likely to cause death within 5 years.
This session will discuss:
1. The rationale for the study;
2. Screening for dementia at baseline to
exclude individuals with the condition;
3. Monitoring methods for the detection of
cognitive decline and incident dementia;
4. Adjudication methods;
5. Substudies related to dementia outcomes
(e.g. MRI studies).
To March 2013, 2 101 Australian GPs have
registered in the study of whom 1 501 have
commenced recruiting participants, 52 351
individuals have been phone screened and 11
998 participants have been randomised.
Chancellor 5
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LeIsURe
HEaRt FOuNdatiON WalkiNg ­
aCtivE bOdy, aCtivE bRaiN
helen Morley
National Heart Foundation
Michelle Wilson
National Program Manager - Heart Foundation
Walking, National Heart Foundation
Lenore de la Perrelle
Manager Dementia Learning and Development
Unit, ACH Group
Regular physical activity has a number of
benefits for our health and promotes a sense
of enjoyment of life. Walking is the most
preferred physical activity option in Australia
and is a highly appropriate and adaptable
activity for people with dementia.
Heart Foundation Walking (HFW) is Australia's
largest free group walking program. Funded
by Alzheimer's Australia through the National
Quality Dementia Care Initiative, HFW ­
Active Body, Active Brain aims to increase
the number of people with dementia and their
carers participating in walking. In partnership
with the ACH Group, program resources and
approaches have been modified to increase
access to HFW for people with dementia
and their carers and reduce the impact of the
symptoms of dementia.
Results from participant's surveys and focus
groups will be presented along with outcomes
of the pilot programs to show the interest
in walking groups for people with dementia
and the areas to be adapted to enable their
inclusion in community walking groups.
Volunteer Walk Organisers have demonstrated
an increased confidence and capacity to
support people with dementia to participate in
HFW.