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Improve Performance, Save Solvent
When chromatographic column performance improves you can decrease your analysis time
and also decrease your overall solvent consumption without compromising your separa-
tions. Use Kinetex
®
Core-Shell Technology to dramatically decrease the solvent consump-
tion in your laboratory and increase sample throughput.
Example Method Consumption
Less Solvent Consumption with Kinetex Column
Conditions for both columns:
Mobile Phase: A: 20 mM Potassium phosphate pH 7
B: Methanol / Acetonitrile (50:50)
A/B (48:52)
Temperature: 40 ºC
Detection: UV @ 254 nm
Sample: 1. Tianeptine
2. Desmethyldoxepin
3. Protriptyline
4. Desipramine
5. Imipramine
6. Amoxapine
7. Doxepin
8. Nortriptyline
9. Amitriptyline
10. Clomipramine
Column: Traditional 5 µm C18
Dimensions: 250 x 4.6 mm
Flow Rate: 1.0 mL/min
Column: Kinetex 2.6 µm C18
Dimensions: 50 x 2.1 mm
Flow Rate: 1.0 mL/min
0
18243
1
2
3
20
40
60
80
100
120
min
4
5
6
7
8
9
10
110 mL
solvent per run!
< 4 mL
solvent per run!
App ID 18243
1
2
3
4
min
0
18245
1
2
3
4
5
6
7
8
9
10
App ID 18245
TM
2.6
µm
Comparative separations may not be representative of all applications.
Phenomenex
l
WEB: www.phenomenex.com