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RESEARCH DIRECTORY
Dr. Symons has focused his
research on the molecular
dissection of signaling
pathways that are responsible
for tumor cell invasion
and survival, with current
emphasis on brain tumors.
The research focuses on
two types of malignant
tumors: glioblastoma and
medulloblastoma.
Dr. Soffer studies mechanisms
of metastasis and resistance
to anti-angiogenic therapies in
pediatric soft tissue sarcomas.
The goal is to prevent micro-
metastatic disease following
tumor resection in a host
of pediatric solid tumors.
Dr. Szeszko uses MRI to
study the brains of patients
who suffer from psychiatric
disorders in order to identify
structural and functional
abnormalities that play a
role in the pathogenesis
of disorders including
schizophrenia, bipolar
disorder and obsessive-
compulsive disorder. He
also identifies neuroimaging
predictors of treatment
response and outcome.
The research focus of Dr.
Son is on a pathogenic
pathway in lupus; specifically
the fundamental tolerance
role of complement C1q in
immune system. She studies
the function of LAIR-1 and
manipulating C1q and LAIR-
1 for down-regulation of
myeloid cells to improve the
severity of lupus.
Dr. Talwar studies
translational research in
pulmonary medicine with
a focus on pulmonary
hypertension and advanced
lung disease. He also
researches comorbidities
of these diseases and their
impact on patients' mental
health and quality of life.
Dr. Singhal's research is
focused on studying the
mechanism of the progression
of renal lesions in patients
with HIV-associated
nephropathy (HIVAN), a
complication of AIDS. He also
studies the effects of opiates
and ethanol on T cell injury.
Dr. Tracey's research
focus is inflammation,
the physiological and
immunological response to
infection and injury and the
mechanism by which neurons
control the immune system.
Most recently, he has made
discoveries in bioelectronic
medicine. Bioelectronic
medicine tells nerves to
produce the natural chemicals
the body uses to cure itself.
Dr. Steinberg's research is
primarily focused on diseases
of the airway caused by
human papillomaviruses
(HPVs). One of these diseases
is recurrent respiratory
papillomatosis (RRP). She also
studies HPV-induced head
and neck cancers.
MARC H. SYMONS, PHD
Oncology & Cell Biology
SAMUEL Z. SOFFER, MD
Oncology & Cell Biology
PHILIP R. SZESZKO, PHD
Psychiatric Neuroscience
MYOUNGSUN SON, PHD
Autoimmune &
Musculoskeletal Disease
ARUNABH TALWAR, MD
Heart & Lung Research
PRAVIN C. SINGHAL, MD
Immunology & Inflammation
KEVIN J. TRACEY, MD
Biomedical Science
BETTIE M. STEINBERG, PHD
Oncology & Cell Biology
32
2015 ANNUAL REPORT