![]() focuses on degeneration and regeneration of musculoskeletal tissues, particularly intervertebral disc, articular cartilage and tendonous tissues. Her lab uses tools of bioengineering, cellular and molecular biology and animal physiology to develop new treatment strategies for repairing arthritic and diseased musculoskeletal tissues. Chavan's research is in bioelectronic medicine, and developing knowledge about the neuroanatomical pathways and neural codes in the vagus nerve that underlie its regulation of the immune response. She also works to develop targeted therapeutics for the treatment of long- term effects of inflammatory diseases. is on the early identification and treatment of adolescents and young adults who are considered to be at-risk for developing serious psychiatric illness as adults, especially schizophrenia and other psychotic disorders. She directs the Recognition and Prevention (RAP) program. activation and maturation of B-lymphocytes, and uses this information to develop and test new diagnostics and treatments for patients suffering from chronic lymphocytic leukemia (CLL), a B-lymphocyte cancer residing in the blood, bone marrow and lymphoid tissues. His studies have impacted CLL patient prognosis and care. identification and treatment of patients with severe psychiatric disorders. His areas of focus include schizophrenia-spectrum, mood-spectrum and aggressive-spectrum disorders. He is also an expert in the risk-benefit evaluation of psychotropic medications. are currently focused on understanding the molecular basis for the development of B cell chronic lymphocytic leukemia (CLL). More broadly, he is interested in B cell biology, particularly B cell maturation and development and its relationship to disease and autoimmunity. Dr. Davidson are focused on pathogenesis and therapy of lupus. Her lab's first goal is to understand more about the regulation of autoantibody- producing B cells and to use newly-discovered pathways of immune activation to design and test novel therapies for lupus. research is to improve the understanding of Alzheimer's disease to allow for the discovery, development and testing of effective therapies. Recent work focuses on activation of cell cycle mechanisms in Alzheimer's disease and modifications of the microtubule associated protein tau as a reporter for signal transduction in the human brain. |